Eosinophilic esophagitis and risk of incident major adverse cardiovascular events: a nationwide matched cohort study.

ABSTRACT:

Background

Inflammatory diseases have been associated with an increased cardiovascular risk. However, data on incident major adverse cardiovascular events (MACE) from large population-based cohorts of patients with eosinophilic esophagitis (EoE) is lacking.

Methods

This study included all Swedish adults with EoE without a record of previous cardiovascular disease (CVD) (1990-2017, N = 1546) with follow-up until 2019. Individuals with EoE were identified from prospectively recorded histopathology reports from all Swedish pathology departments (n = 28). EoE patients were matched at index date for age, sex, calendar year and county with up to five general population reference individuals (N = 7281) without EoE or CVD. Multivariable-adjusted hazard ratios (aHRs) for MACE (ischem

SUBMITTER: Forss A 

PROVIDER: S-EPMC11199241 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature