The minimally important difference for the Xerostomia Inventory among Sjogren's disease patients.

ABSTRACT:

Objective

Until now, the clinically relevant improvement for the Xerostomia Inventory (XI) has not been defined. Therefore, our aim was to determine the Minimally Important Difference (MID) of the XI for improvement in dry-mouth symptoms in SjD patients.

Method

The study recruited 34 SjD patients who underwent sialendoscopy of major salivary glands and 15 SjD patients in a nonintervention control group. XI scores were assessed at several time points. The MID was determined from the mean difference in XI scores between the groups with and without improvement.

Results

In the control group, no significant XI score changes were seen. In the sialendoscopy group, a clinically relevant XI score change of four scale points was identified after 1 week. For a prolonged duration

SUBMITTER: Assy Z 

PROVIDER: S-EPMC11199375 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature