The MYB-like protein MylA contributes to conidiogenesis and conidial germination in Aspergillus nidulans.

ABSTRACT: Myeloblastosis (MYB)-like proteins are a family of highly conserved transcription factors in animals, plants, and fungi and are involved in the regulation of mRNA expression of genes. In this study, we identified and characterized one MYB-like protein in the model organism Aspergillus nidulans. We screened the mRNA levels of genes encoding MYB-like proteins containing two MYB repeats in conidia and found that the mRNA levels of four genes including flbD, cicD, and two uncharacterized genes, were high in conidia. To investigate the roles of two uncharacterized genes, AN4618 and AN10944, deletion mutants for each gene were generated. Our results revealed that AN4618 was required for fungal development. Therefore, we further investigated the role of AN4618, named as mylA, encoding the MYB-lik

SUBMITTER: Son YE 

PROVIDER: S-EPMC11199622 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature