Exploring molecular targets: herbal isolates in cervical cancer therapy.

ABSTRACT:

Objective

Cervical cancer (CxCa) stands as a significant global health challenge, ranking fourth in cancer-related mortality among the female population. While chemotherapy regimens have demonstrated incremental progress in extending overall survival, the outlook for recurrent CxCa patients remains disheartening. An imperative necessity arises to delve into innovative therapeutic avenues, with molecular targeted therapy emerging as a promising candidate. Previous investigations have shed light on the therapeutic effectiveness of five distinct herbal compounds, epicatechin, curcumin, myricetin, jatrorrhizine, and arborinine, within the context of CxCa.

Methods

A systems biology approach was employed to discern differentially expressed genes (DEGs) in CxCa tissues relative to

SUBMITTER: Ahmadi M 

PROVIDER: S-EPMC11201312 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature