Development of topical silver nano gel formulation of Bixin: Characterization, and evaluation of anticancer activity.

ABSTRACT:

Objective

Skin cancer refers to the pathological condition characterized by the proliferation of atypical skin cells in an uncontrolled manner. Plant-based products such as bixin although show promising anticancer properties, but maintaining their stability in a formulation is a difficult task. The objective of the research is to formulate a silver nanoparticle gel preparation of bixin and evaluate its anticancer properties.

Methods

The extract from Bixa orellana seed was prepared by hot extraction technique to isolate the active ingredient, bixin. A green synthesis approach was utilized for preparing the silver nanoparticle gel of bixin (BOAgNPs). Characterization of silver nanoparticles was done using FTIR, scanning electron microscopy, compatibility study, homogene

SUBMITTER: Patil SS 

PROVIDER: S-EPMC11201344 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature