A novel surgical scheme for hepatectomy in hepatocellular carcinoma patients with clinically significant portal hypertension.

ABSTRACT:

Objective

Clinically significant portal hypertension (CSPH) seriously affects the feasibility and safety of surgical treatment for hepatocellular carcinoma (HCC) patients. The aim of this study was to establish a new surgical scheme defining risk classification of post-hepatectomy liver failure (PHLF) to facilitate the surgical decision-making and identify suitable candidates for individual hepatectomy among HCC patients with CSPH.

Backgrounds

Hepatectomy is the preferred treatment for HCC. Surgeons must maintain a balance between the expected oncological outcomes of HCC removal and short-term risks of severe PHLF and morbidity. CSPH aggravates liver decompensation and increases the risk of severe PHLF thus complicating hepatectomy for HCC.

Methods

Multivariate logist

SUBMITTER: Ye JZ 

PROVIDER: S-EPMC11202348 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature