Identification of transposable element families from pangenome polymorphisms.

ABSTRACT:

Background

Transposable Elements (TEs) are segments of DNA, typically a few hundred base pairs up to several tens of thousands bases long, that have the ability to generate new copies of themselves in the genome. Most existing methods used to identify TEs in a newly sequenced genome are based on their repetitive character, together with detection based on homology and structural features. As new high quality assemblies become more common, including the availability of multiple independent assemblies from the same species, an alternative strategy for identification of TE families becomes possible in which we focus on the polymorphism at insertion sites caused by TE mobility.

Results

We develop the idea of using the structural polymorphisms found in pangenomes to create a libr

SUBMITTER: Sierra P 

PROVIDER: S-EPMC11202377 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature