Hydrogen sulfide and its role in female reproduction.

ABSTRACT: Hydrogen sulfide (H₂S) is a gaseous signaling molecule produced in the body by three enzymes: cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3-MST). H₂S is crucial in various physiological processes associated with female mammalian reproduction. These include estrus cycle, oocyte maturation, oocyte aging, ovulation, embryo transport and early embryo development, the development of the placenta and fetal membranes, pregnancy, and the initiation of labor. Despite the confirmed presence of H₂S-producing enzymes in all female reproductive tissues, as described in this review, the exact mechanisms of H₂S action in these tissues remain in most cases unclear. Therefore, this review aims to summarize

SUBMITTER: Pilsova A 

PROVIDER: S-EPMC11202402 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature