Free Salivary Amino Acid Profile in Breast Cancer: Clinicopathological and Molecular Biological Features.

ABSTRACT: The study of salivary amino acid profiles has attracted the attention of researchers, since amino acids are actively involved in most metabolic processes, including breast cancer. In this study, we analyzed the amino acid profile of saliva in a sample including all molecular biological subtypes of breast cancer to obtain a more complete picture and evaluate the potential utility of individual amino acids or their combinations for diagnostic purposes. This study included 116 patients with breast cancer, 24 patients with benign breast disease, and 25 healthy controls. From all patients, strictly before the start of treatment, saliva samples were collected, and the quantitative content of 26 amino acids was determined. Statistically significant differences between the three groups are shown i

SUBMITTER: Bel'skaya LV 

PROVIDER: S-EPMC11202888 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature