Combination effect of optical defocus and low dose atropine in myopia control: Study protocol for a randomized clinical trial.

ABSTRACT:

Background

Myopia, characterized by excessive axial elongation of the eyeball, increases risks of having sight-threatening diseases and impose a financial burden to healthcare system. Although myopic control interventions showed their effectiveness in slowing progression, the efficacy varies between individuals and does not completely halt progression. The study aims to investigate the efficacy of combining 0.01% atropine administered twice daily with optical defocus for myopia control in schoolchildren.

Methods and design

This is a prospective, parallel-group, single-blinded, randomized, active-control trial (ClinicalTrials.gov identifier: NCT06358755). Myopic schoolchildren with no previous myopic control interventions aged between 7 to 12 years will be recruited. They wil

SUBMITTER: Chun RKM 

PROVIDER: S-EPMC11206955 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature