Synthesis and Optical Properties of a Novel Hybrid Nanosystem Based on Covalently Modified nSiO₂ Nanoparticles with a Curcuminoid Molecule.

ABSTRACT: A new curcuminoid molecule (3) has been designed and synthesized, containing a central -(CH₂)₂-COOH chain at the α carbon of the keto-enol moiety in the structure. The carboxylic acid group is added to react with exposed amino groups on silica oxide nanoparticles (nSiO₂), forming an amide bond to attach the curcuminoid moiety to the nSiO₂ covalently. The Kaiser test quantifies the functionalization degree, yielding 222 μmol of curcuminoid per gram of nanoparticles. The synthesized hybrid nanosystem, nSiO₂-NHCO-CCM, displays significant emission properties, with a maximum emission at 538 nm in dichloromethane, similar to curcuminoid 1 (without the central chain), which emits at 565 nm in the same solvent. Solvent-induced s

SUBMITTER: Parra-Munoz N 

PROVIDER: S-EPMC11207103 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature