Belief Updating in Subclinical and Clinical Delusions.

ABSTRACT:

Background and hypothesis

Current frameworks propose that delusions result from aberrant belief updating due to altered prediction error (PE) signaling and misestimation of environmental volatility. We aimed to investigate whether behavioral and neural signatures of belief updating are specifically related to the presence of delusions or generally associated with manifest schizophrenia.

Methods

Our cross-sectional design includes human participants (n[female/male] = 66[25/41]), stratified into four groups: healthy participants with minimal (n = 22) or strong delusional-like ideation (n = 18), and participants with diagnosed schizophrenia with minimal (n = 13) or strong delusions (n = 13), resulting in a 2 × 2 design, which allows to test fo

SUBMITTER: Fromm S 

PROVIDER: S-EPMC11207849 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature