Prefrontal cortex oxygenation during a mentally fatiguing task in normoxia and hypoxia.

ABSTRACT: Mental fatigue (MF) and hypoxia impair cognitive performance through changes in brain hemodynamics. We want to elucidate the role of prefrontal cortex (PFC)-oxygenation in MF. Twelve participants (22.9 ± 3.5 years) completed four experimental trials, (1) MF in (normobaric) hypoxia (MF_HYP) (3.800 m; 13.5%O₂), (2) MF in normoxia (MF_NOR) (98 m; 21.0%O₂), (3) Control task in HYP (CON_HYP), (4) Control in NOR (CON_NOR). Participants performed a 2-back task, Digit Symbol Substitution test and Psychomotor Vigilance task before and after a 60-min Stroop task or an emotionally neutral documentary. Brain oxygenation was measured through functional Near Infrared Spectroscopy. Subjective feelings of MF and physiological measures (heart rate, oxygen saturation, blood glucose and

SUBMITTER: De Wachter J 

PROVIDER: S-EPMC11208267 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature