The photoactivated antifungal activity and possible mode of action of sodium pheophorbide a on <i>Diaporthe mahothocarpus</i> causing leaf spot blight in <i>Camellia oleifera</i>.

ABSTRACT:

Introduction

Sodium pheophorbide a (SPA) is a natural plant-derived photosensitizer, with high photoactivated antifungal activity against some phytopathogenic fungi. However, its fungicidal effect on Diaporthe mahothocarpus, a novel pathogen that causes Camellia oleifera leaf spot blight, is unclear.

Methods

In the present study, we explored its inhibitory effects on spore germination and mycelial growth of D. mahothocarpus. Then we determined its effects on the cell membrane, mycelial morphology, redox homeostasis, and cell death through bioassay. Finally, RNA-seq was used further to elucidate its mode of action at the transcriptional level.

Results

We found that SPA effectively inhibited the growth of D. mahothocarpus, with half-maximal e

SUBMITTER: Shi XL 

PROVIDER: S-EPMC11208333 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature