Distinct grey and white matter changes are associated with the phenomenology of visual hallucinations in Lewy Body Disease.

ABSTRACT: Visual hallucinations in Lewy body disease (LBD) can be differentiated based on phenomenology into minor phenomena (MVH) and complex hallucinations (CVH). MVH include a variety of phenomena, such as illusions, presence and passage hallucinations occurring at early stages of LBD. The neural mechanisms of visual hallucinations are largely unknown. The hodotopic model posits that the hallucination state is due to abnormal activity in specialized visual areas, that occurs in the context of wider network connectivity alterations and that phenomenology of VH, including content and temporal characteristics, may help identify brain regions underpinning these phenomena. Here we investigated both the topological and hodological neural basis of visual hallucinations integrating grey and white matter

SUBMITTER: D'Antonio F 

PROVIDER: S-EPMC11208453 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature