Macrophage-derived CD36 + exosome subpopulations as novel biomarkers of Candida albicans infection.

ABSTRACT: Invasive candidiasis (IC) is a notable healthcare-associated fungal infection, characterized by high morbidity, mortality, and substantial treatment costs. Candida albicans emerges as a principal pathogen in this context. Recent academic advancements have shed light on the critical role of exosomes in key biological processes, such as immune responses and antigen presentation. This burgeoning body of research underscores the potential of exosomes in the realm of medical diagnostics and therapeutics, particularly in relation to fungal infections like IC. The exploration of exosomal functions in the pathophysiology of IC not only enhances our understanding of the disease but also opens new avenues for innovative therapeutic interventions. In this investigation, we focus on exosomes (Exos) se

SUBMITTER: Li S 

PROVIDER: S-EPMC11208550 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature