Multivitamin Use and Mortality Risk in 3 Prospective US Cohorts.

ABSTRACT:

Importance

One in 3 US adults uses multivitamins (MV), with a primary motivation being disease prevention. In 2022, the US Preventive Services Task Force reviewed data on MV supplementation and mortality from randomized clinical trials and found insufficient evidence for determining benefits or harms owing, in part, to limited follow-up time and external validity.

Objective

To estimate the association of MV use with mortality risk, accounting for confounding by healthy lifestyle and reverse causation whereby individuals in poor health initiate MV use.

Design, setting, and participants

This cohort study used data from 3 prospective cohort studies in the US, each with baseline MV use (assessed from 1993 to 2001), and follow-up MV use (assessed from 1998 to 2004), extend

SUBMITTER: Loftfield E 

PROVIDER: S-EPMC11208972 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature