Real-World Assessment of Recommended COVID-19 Vaccination Waiting Period after Chemotherapy.

ABSTRACT: There is a knowledge gap concerning the proper timing for COVID-19 vaccination in cancer patients undergoing chemotherapy. We aimed to evaluate the suitability of the guidelines that recommend waiting at least three months after undergoing chemotherapy before receiving a COVID-19 vaccine. This retrospective cohort study used aggregated data from the TriNetX US Collaboratory network. Participants were grouped into two groups based on the interval between chemotherapy and vaccination. The primary outcome assessed was infection risks, including COVID-19; skin, intra-abdominal, and urinary tract infections; pneumonia; and sepsis. Secondary measures included healthcare utilization and all causes of mortality. Kaplan-Meier analysis and the Cox proportional hazard model were used to calculate the

SUBMITTER: Cheng KW 

PROVIDER: S-EPMC11209144 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature