First Characterization of Acinetobacter baumannii-Specific Filamentous Phages.

ABSTRACT: Filamentous bacteriophages belonging to the order Tubulavirales, family Inoviridae, significantly affect the properties of Gram-negative bacteria, but filamentous phages of many important pathogens have not been described so far. The aim of this study was to examine A. baumannii filamentous phages for the first time and to determine their effect on bacterial virulence. The filamentous phages were detected in 15.3% of A. baumannii strains as individual prophages in the genome or as tandem repeats, and a slightly higher percentage was detected in the culture collection (23.8%). The phylogenetic analyses revealed 12 new genera within the Inoviridae family. Bacteriophages that were selected and isolated showed structural and genomic characteristics of the fam

SUBMITTER: Narancic J 

PROVIDER: S-EPMC11209303 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature