Field Trials of Live and Inactivated Camelpox Vaccines in Kazakhstan.

ABSTRACT: An outbreak of camelpox occurred in the Mangistau region of Kazakhstan in 2019. To control the outbreak of camelpox and to prevent its further spread to other regions, camels were vaccinated using live and inactivated camelpox vaccines produced in Kazakhstan. To evaluate the efficacy of these camelpox vaccines in the field, vaccine trials used 172 camels on camel farms in the Beineu district. Of these, 132 camels were vaccinated using a live attenuated camelpox vaccine and 40 camels were vaccinated using an inactivated vaccine to observe immunogenicity and safety. The live vaccine was inoculated into camels by scarification at a dose of 5 × 10⁴ EID₅₀, and the inactivated vaccine was injected intramuscularly at 5 mL twice, with an interval of 35 days. During the safety

SUBMITTER: Mambetaliyev M 

PROVIDER: S-EPMC11209348 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature