Identification of a Novel Aflatoxin B₁-Degrading Strain, <i>Bacillus halotolerans</i> DDC-4, and Its Response Mechanisms to Aflatoxin B₁.

ABSTRACT: Aflatoxin B₁ (AFB₁) contamination is a food safety issue threatening human health globally. Biodegradation is an effective method for overcoming this problem, and many microorganisms have been identified as AFB₁-degrading strains. However, the response mechanisms of these microbes to AFB₁ remain unclear. More degrading enzymes, especially of new types, need to be discovered. In this study, a novel AFB₁-degrading strain, DDC-4, was isolated using coumarin as the sole carbon source. This strain was identified as Bacillus halotolerans through physiological, biochemical, and molecular methods. The strain's degradation activity was predominantly attributable to thermostable extracellular proteins (degradation rate remained approximat

SUBMITTER: Guo J 

PROVIDER: S-EPMC11209560 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature