Time-Resolved Ion Mobility Spectrometry with a Stop Flow Confined Volume Reaction Region.

ABSTRACT: An ion source concept is described where the sample flow is stopped in a confined volume of an ion mobility spectrometer creating time-dependent patterns of ion patterns of signal intensities for ions from mixtures of volatile organic compounds and improved signal-to-noise rate compared to conventional unidirectional drift gas flow. Hydrated protons from a corona discharge were introduced continuously into the confined volume with the sample in air at ambient pressure, and product ions were extracted continuously using an electric field for subsequent mobility analysis. Ion signal intensities for protonated monomers and proton bound dimers were measured and computationally extracted using mobilities from mobility spectra and exhibited distinct times of appearance over 30 s or more after sa

SUBMITTER: Anttalainen O 

PROVIDER: S-EPMC11209659 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature