Single-shot diffusion trace spectroscopic imaging using radial echo planar trajectories.

ABSTRACT:

Purpose

Demonstrate the feasibility and evaluate the performance of single-shot diffusion trace-weighted radial echo planar spectroscopic imaging (Trace DW-REPSI) for quantifying the trace ADC in phantom and in vivo using a 3T clinical scanner.

Theory and methods

Trace DW-REPSI datasets were acquired in 10 phantom and 10 healthy volunteers, with a maximum b-value of 1601 s/mm² and diffusion time of 10.75 ms. The self-navigation properties of radial acquisitions were used for corrections of shot-to-shot phase and frequency shift fluctuations of the raw data. In vivo trace ADCs of total NAA (tNAA), total creatine (tCr), and total choline (tCho) extrapolated to pure gray and white matter fractions were compared, as well as trace ADCs estimated in voxels within white

SUBMITTER: Saucedo A 

PROVIDER: S-EPMC11209789 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature