MR signature matching (MRSIGMA) implementation for true real-time free-breathing volumetric imaging with sub-200 ms latency on an MR-Linac.

ABSTRACT:

Purpose

Develop a true real-time implementation of MR signature matching (MRSIGMA) for free-breathing 3D MRI with sub-200 ms latency on the Elekta Unity 1.5T MR-Linac.

Methods

MRSIGMA was implemented on an external computer with a network connection to the MR-Linac. Stack-of-stars with partial k_z sampling was used to accelerate data acquisition and ReconSocket was employed for simultaneous data transmission. Movienet network computed the 4D MRI motion dictionary and correlation analysis was used for signature matching. A programmable 4D MRI phantom was utilized to evaluate MRSIGMA with respect to a ground-truth translational motion reference. In vivo validation was performed on patients with pancreatic cancer, where 15 patients were employed to train Movienet and

SUBMITTER: Siddiq S 

PROVIDER: S-EPMC11209806 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature