Runs of homozygosity and selection signature analyses reveal putative genomic regions for artificial selection in layer breeding.

ABSTRACT:

Background

The breeding of layers emphasizes the continual selection of egg-related traits, such as egg production, egg quality and eggshell, which enhance their productivity and meet the demand of market. As the breeding process continued, the genomic homozygosity of layers gradually increased, resulting in the emergence of runs of homozygosity (ROH). Therefore, ROH analysis can be used in conjunction with other methods to detect selection signatures and identify candidate genes associated with various important traits in layer breeding.

Results

In this study, we generated whole-genome sequencing data from 686 hens in a Rhode Island Red population that had undergone fifteen consecutive generations of intensive artificial selection. We performed a genome-wide ROH analysis an

SUBMITTER: Li X 

PROVIDER: S-EPMC11210043 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature