Use of ketamine in Super Refractory Status Epilepticus: a systematic review.

ABSTRACT:

Objective

This review specifically investigates ketamine's role in SRSE management.

Methods

PubMed, EMBASE, and Google Scholar databases were searched from inception to May 1st, 2023, for English-language literature. Inclusion criteria encompassed studies on SRSE in humans of all ages and genders treated with ketamine.

Results

In this systematic review encompassing 19 studies with 336 participants, age ranged from 9 months to 86 years. Infections, anoxia, and metabolic issues emerged as the common causes of SRSE, while some cases had unknown origins, termed as NORSE (New Onset RSE) or FIRESs (Febrile Infection-Related Epilepsy Syndrome). Most studies categorized SRSE cases into convulsive (N = 105) and non-convulsive (N = 197). Ketamine was used after failed antiepile

SUBMITTER: Adhikari A 

PROVIDER: S-EPMC11210084 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature