The association between diabetes mellitus and prostate cancer: a meta-analysis and Mendelian randomization.

ABSTRACT:

Background

Prostate cancer is one of the most common types of cancer in the US, and it has a high mortality rate. Diabetes mellitus is also a dangerous health condition. While some studies have examined the relationship between diabetes mellitus and the risk of prostate cancer, there is still some debate on the matter. This study aims to carefully assess the relationship between prostate cancer and diabetes from both real-world and genetic-level data.

Methods

This meta-analysis was conducted following the PRISMA 2020 reporting guidelines. The study searched three databases including Medline, Embase and Cochrane. The studies about the incidence risk of prostate cancer with diabetes mellitus were included and used to evaluate the association. The odds ratio (OR), risk ratio (R

SUBMITTER: Ye GC 

PROVIDER: S-EPMC11210264 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature