Aspergillus fumigatus-a systematic review to inform the World Health Organization priority list of fungal pathogens.

ABSTRACT: Recognizing the growing global burden of fungal infections, the World Health Organization established a process to develop a priority list of fungal pathogens (FPPL). In this systematic review, we aimed to evaluate the epidemiology and impact of invasive infections caused by Aspergillus fumigatus to inform the first FPPL. The pre-specified criteria of mortality, inpatient care, complications and sequelae, antifungal susceptibility, risk factors, preventability, annual incidence, global distribution, and emergence were used to search for relevant articles between 1 January 2016 and 10 June 2021. Overall, 49 studies were eligible for inclusion. Azole antifungal susceptibility varied according to geographical regions. Voriconazole susceptibility rates of 22.2% were reported from the Netherlan

SUBMITTER: Morrissey CO 

PROVIDER: S-EPMC11210617 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature