Investigating home-based opioid use among youth with sickle cell disease using ecological momentary assessment.

ABSTRACT:

Background

Opioids are a common and essential treatment for acute sickle cell disease (SCD) pain. However, opioids carry well-known adverse side effects, including potential development of hyperalgesia and nociplastic pain. We characterized opioid use in youth with SCD using ecological momentary assessment (EMA) data, and investigated the relationships between home-based opioid use, pain, and a range of biopsychosocial factors.

Method

Eighty-eight youth with SCD (aged 8-17 years) completed EMAs assessing home-based opioid use, pain, and related factors. Analyses consisted of descriptive and multilevel logistic regression to predict daily home opioid use.

Results

Youth averaged 3.64 weeks of EMAs. Approximately 35% of the sample (n = 31) took an opioid during the EMA p

SUBMITTER: Valrie C 

PROVIDER: S-EPMC11211048 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature