Rapid rebalancing of co-tuned ensemble activity in the auditory cortex.

ABSTRACT: Sensory information is represented by small varying neuronal ensembles in sensory cortices. In the auditory cortex (AC) repeated presentations of the same sound activate differing ensembles indicating high trial-by trial variability in activity even though the sounds activate the same percept. Efficient processing of complex acoustic signals requires that these sparsely distributed neuronal ensembles actively interact in order to provide a constant percept. Thus, the differing ensembles might interact to process the incoming sound inputs. Here, we probe interactions within and across ensembles by combining in vivo 2-photon Ca²⁺ imaging and holographic optogenetic stimulation to study how increased activity of single cells level affects the cortical network. We stimulated

SUBMITTER: Kang H 

PROVIDER: S-EPMC11212947 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature