Efficacy and effectiveness of COVID-19 vaccines in Africa: A systematic review.

ABSTRACT:

Background

Data on COVID-19 vaccine effectiveness to support regional vaccine policy and practice are limited in Africa. Thus, this review aimed to evaluate the efficacy and effectiveness of COVID-19 vaccines administered in Africa.

Methods

We systematically searched peer-reviewed randomized controlled trials (RCTs), prospective and retrospective cohort studies, and case-control studies that reported on VE in Africa. We carried out a risk of bias assessment, and the findings of this review were synthesized and presented in a narrative form, including tables and figures. The synthesis was focused on COVID-19 VE against various levels of the disease condition and outcomes (infection, hospitalization or critical, and death), time points, and variants of concern.

Results

SUBMITTER: Raji T 

PROVIDER: S-EPMC11213354 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature