FUT11 expression in gastric cancer: its prognostic significance and role in immune regulation.

ABSTRACT:

Background

Gastric cancer (GC) is a malignant digestive tract tumor with a high recurrence rate and poor prognosis. Fucosylation is important in tumor glycosylation, in which the key enzyme is fucosyltransferase (FUT). FUT11 is a member of the fucosyltransferase family and has been closely associated with the development of multiple cancers. However, the specific relationship between FUT11 and GC prognosis and its molecular mechanism has not been fully studied. This study explored FUT11 expression, clinical correlation, and its role in GC occurrence and development to deepen understanding of its function.

Methods

FUT11 expression in 33 cancers was preliminarily analyzed using the Tumor Immunoassay Resource (TIMER2.0) database. FUT11 expression in GC was evaluated using The C

SUBMITTER: Huang Y 

PROVIDER: S-EPMC11213843 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature