Novel computerized measure of apathy associates with care partner burden and instrumental activities of daily living in Parkinson's disease.

ABSTRACT:

Background

Impairment in goal-directed behavior (GDB) contributes to apathy, a prevalent syndrome in Parkinson's disease (PD). The Philadelphia Apathy Computerized Task (PACT) is a performance-based measure of GDB that may be less confounded by reduced patient insight, cognitive impairment, and care partner burnout.

Objective

To examine how the PACT is related to patient function and care partner burden.

Methods

PD patients with normal cognition (n = 19) or mild cognitive impairment (n = 14) and their care partners were recruited. Participants completed the PACT, a computerized paradigm consisting of subtasks specific to each component of GDB: initiation, motivation, and planning. Care partners completed the Zarit Burden Interview (ZBI) and the Penn Parkinson's Daily

SUBMITTER: Liu J 

PROVIDER: S-EPMC11214727 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature