Characterising HIV-1 transmission in Victoria, Australia: a molecular epidemiological study.

ABSTRACT:

Background

In Australia the incidence of HIV has declined steadily, yet sustained reduction of HIV transmission in this setting requires improved public health responses. As enhanced public health responses and prioritisation of resources may be guided by molecular epidemiological data, here we aimed to assess the applicability of these approaches in Victoria, Australia.

Methods

A comprehensive collection of HIV-1 pol sequences from individuals diagnosed with HIV in Victoria, Australia, between January 1st 2000 and December 31st 2020 were deidentified and used as the basis of our assessment. These sequences were subtyped and surveillance drug resistance mutations (SDRMs) identified, before definition of transmission groups was performed using HIV-TRACE (0.4.4). Phylod

SUBMITTER: Taiaroa G 

PROVIDER: S-EPMC11215101 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature