Disseminated Acanthamoeba castellanii infection in a patient with AIDS: a case report and literature review.

ABSTRACT:

Background

Acanthamoeba castellanii infection is a rare condition primarily occurring in immunocompromised patients with extremely high mortality. Currently, there is no standard treatment for this condition, and successful treatment reports are scarce.

Case presentation

We present a case of Acanthamoeba castellanii infection in a 63-year-old female patient with AIDS, who was admitted to our hospital with symptoms of fever, skin ulcers, subcutaneous nodules, and food regurgitation from the nose while eating. After initial empirical treatment failed, a biopsy of the subcutaneous nodule was performed, and metagenomic next-generation sequencing (mNGS) technology was used to detect pathogenic microorganisms in both the biopsy specimen and blood samples. The results

SUBMITTER: Jiang Q 

PROVIDER: S-EPMC11215114 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature