The clinical and predictive value of ¹⁸F-FDG PET/CT metabolic patterns in a clinical Chinese cohort with autoimmune encephalitis.

ABSTRACT:

Aims

To investigate the diagnostic and predictive role of ¹⁸F-FDG PET/CT in patients with autoimmune encephalitis (AE) as a whole group.

Methods

Thrty-five patients (20 females and 15 males) with AE were recruited. A voxel-to-voxel semi-quantitative analysis based on SPM12 was used to analyze ¹⁸F-FDG PET/CT imaging data compared to healthy controls. Further comparison was made in different prognostic groups categorized by modified Rankin Scale (mRS).

Results

In total, 24 patients (68.6%) were tested positive neuronal antibodies in serum and/or CSF. Psychiatric symptoms and seizure attacks were major clinical symptoms. In the acute stage, 13 patients (37.1%) demonstrated abnormal brain MRI results, while 33 (94.3%) presented abnormal metabolism pa

SUBMITTER: Dai Y 

PROVIDER: S-EPMC11215490 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature