Study of optical rotation based on the molecular structure in fused oligomers of macrocycles.

ABSTRACT: We designed a unique oligomer form in which several helically twisted macrocycles (M- or P-helicity) are arranged through fusion. We investigated the optical rotation of a series of fused oligomers of macrocycles with a difference in the number and arrangement of elements associated with point-chiral auxiliary. Some oligomers cooperatively attained a situation where an identical sense of twisting was preferred throughout the entire molecule. On the basis of these results, we estimated diastereomeric excess induced in each oligomer. We revealed that the molar optical rotation per element was modulated with a rotational angle between elements: an increase via 0° rotational arrangement, a decrease via 180° rotational arrangement, or a decrease via cyclic arr

SUBMITTER: Katoono R 

PROVIDER: S-EPMC11215750 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature