Electrocardiographic tracking of left ventricular hypertrophy in hypertension: incidence and prognostic outcomes from the SPRINT trial.

ABSTRACT:

Background

This study explores the impact of intensive blood pressure (BP) control on left ventricular hypertrophy (LVH) incidence and evaluates the prognostic implications of LVH status (pre-existing/new-onset/persistent/regression) using Systolic Blood Pressure Intervention Trial (SPRINT) Electrocardiogram Data.

Methods

Poisson regression was used to assess new-onset LVH and LVH regression rates. Multivariable-adjusted Cox proportional hazard models determined the risk of adverse cardiovascular events (ACE), a composite of myocardial infarction (MI), non-MI acute coronary syndrome, stroke, heart failure, or cardiovascular death, alongside safety adverse events.

Results

In 8,016 participants, intensive BP control significantly reduced new-onset LVH (8.27 vs. 14.79 pe

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC11215828 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature