Preoperative serum cholinesterase as a prognostic factor in patients with colorectal cancer.

ABSTRACT:

Aim

Serum cholinesterase (ChE) levels are considered to reflect nutritional status. Although ChE has been well documented as a prognostic factor for some cancers, no clear consensus on its use for colorectal cancer (CRC) has been reached. The aim of this study was to investigate the relationship between preoperative serum ChE and postoperative long-term prognosis in CRC patients.

Methods

A total of 1053 CRC patients who underwent curative surgery were included in this study. The correlations between the preoperative ChE value and overall survival (OS) or cancer-specific survival (CSS) were assessed. By dividing patients into two groups according to their ChE value, OS and CSS were compared between the groups.

Results

Multivariate analysis revealed that the continuous

SUBMITTER: Nakamura K 

PROVIDER: S-EPMC11216785 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature