Does the Relationship between Age and Brain Structure Differ in Youth with Conduct Disorder?

ABSTRACT: Conduct disorder (CD) is characterised by persistent antisocial and aggressive behaviour and typically emerges in childhood or adolescence. Although several authors have proposed that CD is a neurodevelopmental disorder, very little evidence is available about brain development in this condition. Structural brain alterations have been observed in CD, and some indirect evidence for delayed brain maturation has been reported. However, no detailed analysis of age-related changes in brain structure in youth with CD has been conducted. Using cross-sectional MRI data, this study aimed to explore differences in brain maturation in youth with CD versus healthy controls to provide further understanding of the neurodevelopmental processes underlying CD. 291 CD cases (153 males) and 379 healthy contr

SUBMITTER: Koerner S 

PROVIDER: S-EPMC11217071 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature