Preliminary protocol for measuring the reproducibility and accuracy of flow values on digital PET/CT systems in [¹⁵O]H₂O myocardial perfusion imaging using a flow phantom.

ABSTRACT:

Background

Several factors may decrease the accuracy of quantitative PET myocardial perfusion imaging (MPI). It is therefore essential to ensure that myocardial blood flow (MBF) values are reproducible and accurate, and to design systematic protocols to achieve this. Until now, no systematic phantom protocols have been available to assess the technical factors affecting measurement accuracy and reproducibility in MPI.

Materials and methods

We implemented a standard measurement protocol, which applies a flow phantom in order to compare image-derived flow values with respect to a ground truth flow value with [¹⁵O]H₂O MPI performed on both a Discovery MI (DMI-20, GE Healthcare) and a Biograph Vision 600 (Vision-600, Siemens Healthineers) system. Both syste

SUBMITTER: Siekkinen R 

PROVIDER: S-EPMC11217201 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature