Association between gut microbiota and malignant cardiac tumors: A two-sample Mendelian randomization study.

ABSTRACT:

Background

Recent studies provide compelling evidence linking the gut microbiota to most cancers. Nevertheless, further research is required to establish a definitive causal relationship between the gut microbiota and malignant cardiac tumors.

Methods

The genome-wide association studies (GWAS) data on the human gut Microbiota, included in the IEU Open GWAS project, was initially collected by the MiBioGen consortium. It encompasses 14,306 individuals and comprises a total of 5,665,279 SNPs. Similarly, the GWAS data on malignant cardiac tumors, also sourced from the IEU Open GWAS project, was initially stored in the finnGen database, including 16,380,303 SNPs observed within a cohort of 174,108 individuals within the European population. Utilizing a two-sample Mendelian random

SUBMITTER: Song Y 

PROVIDER: S-EPMC11217809 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature