The value of the current histological scores and classifications of ANCA glomerulonephritis in predicting long-term outcome.

ABSTRACT:

Background

Three different histological scores-histopathologic classification (Berden), Renal Risk Score (RRS) and the Mayo Clinic Chronicity Score (MCCS)-for anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis (ANCA-GN) were compared to evaluate their association with patient and kidney prognosis of ANCA-GN.

Methods

Patients aged >18 years with at least 1 year of follow-up and biopsy-proven ANCA-GN entered this retrospective study. Renal biopsies were classified according to Berden's classification, RRS and MCCS. The first endpoint was end-stage kidney disease (ESKD), defined as chronic dialysis or estimated glomerular filtration rate <15 mL/min/1.73 m². The second endpoint was ESKD or death.

Results

Of 152 patients 84 were males, wit

SUBMITTER: Stella M 

PROVIDER: S-EPMC11217817 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature