Helicobacter Pylori infection in children with inflammatory bowel disease: a prospective multicenter study.

ABSTRACT:

Background

The relationship between Helicobacter-pylori(Hp)infection and inflammatory-bowel-disease(IBD) in pediatric-patients remains controversial. We aimed to assess the Hp-infection occurrence in newly-diagnosed pediatric-patients with IBD compared to no-IBD patients. Additionally, we aimed to examine differences in clinical-activity-index(CAI) and endoscopic-severity-score(ESS)between IBD-patients with and without Hp-infection, at baseline and at 1-year-follow-up(FU), after eradication-therapy(ET).

Methods

IBD diagnosis was based on Porto-criteria, and all patients underwent gastroscopy at baseline and 1-year FU. For Crohn's-disease(CD) and ulcerative colitis(UC), IBD-CAI and -ESS were classified using PCDAI/SES-CD and PUCAI/UCEIS, respectively.

Results

76 IBD-pa

SUBMITTER: Dilaghi E 

PROVIDER: S-EPMC11218114 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature