Intraoperative fluid management is not predictive of AKI in major pancreatic surgery: a retrospective cohort study.

ABSTRACT:

Background

Pancreatic surgery is associated with a significant risk for acute kidney injury (AKI) and clinically relevant postoperative pancreatic fistula (CR-POPF). This investigation evaluated the impact of intraoperative volume administration, vasopressor therapy, and blood pressure management on the primary outcome of AKI and the secondary outcome of a CR-POPF after pancreatic surgery.

Methods

This retrospective single-center cohort investigated 200 consecutive pancreatic surgeries (January 2018-December 2021). Patients were categorized for the presence/absence of AKI (Kidney Disease Improving Global Outcomes) and CR-POPF. After univariate analysis, multivariable models were constructed to control for the univariate cofactor differences in the primary and secondary outco

SUBMITTER: Lydon K 

PROVIDER: S-EPMC11218130 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature