Regulatory gene network for coffee-like color morph of TYRP1 mutant of oujiang color common carp.

ABSTRACT:

Background

Neither a TYRP1-mediated highly conserved genetic network underlying skin color towards optimum defense nor the pathological tendency of its mutation is well understood. The Oujiang Color Common Carp (Cyprinus carpio var. color) as a model organism, offering valuable insights into genetics, coloration, aquaculture practices, and environmental health. Here, we performed a comparative skin transcriptome analysis on TYRP1 mutant and wild fishes by applying a conservative categorical approach considering different color phenotypes.

Results

Our results reveal that an unusual color phenotype may be sensitized with TYRP1 mutation as a result of upregulating several genes related to an anti-inflammatory autoimmune system in response to the COMT-mediated catecholamine neur

SUBMITTER: Mandal RN 

PROVIDER: S-EPMC11218255 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature