Vitamin K: a potential missing link in critical illness-a scoping review.

ABSTRACT:

Background

Vitamin K is essential for numerous physiological processes, including coagulation, bone metabolism, tissue calcification, and antioxidant activity. Deficiency, prevalent in critically ill ICU patients, impacts coagulation and increases the risk of bleeding and other complications. This review aims to elucidate the metabolism of vitamin K in the context of critical illness and identify a potential therapeutic approach.

Methods

In December 2023, a scoping review was conducted using the PRISMA Extension for Scoping Reviews. Literature was searched in PubMed, Embase, and Cochrane databases without restrictions. Inclusion criteria were studies on adult ICU patients discussing vitamin K deficiency and/or supplementation.

Results

A total of 1712 articles were scr

SUBMITTER: Paulus MC 

PROVIDER: S-EPMC11218309 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature