Transcriptomic profiling of haloarchaeal denitrification through RNA-Seq analysis.

ABSTRACT: Denitrification, a crucial biochemical pathway prevalent among haloarchaea in hypersaline ecosystems, has garnered considerable attention in recent years due to its ecological implications. Nevertheless, the underlying molecular mechanisms and genetic regulation governing this respiration/detoxification process in haloarchaea remain largely unexplored. In this study, RNA-sequencing was used to compare the transcriptomes of the haloarchaeon Haloferax mediterranei under oxic and denitrifying conditions, shedding light on the intricate metabolic alterations occurring within the cell, such as the accurate control of the metal homeostasis. Furthermore, the investigation identifies several genes encoding transcriptional regulators and potential accessory proteins with putative roles in de

SUBMITTER: Miralles-Robledillo JM 

PROVIDER: S-EPMC11218638 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature