Orbital magnetic resonance imaging of giant cell arteritis with ocular manifestations: a systematic review and individual participant data meta-analysis.

ABSTRACT:

Objectives

We conducted a systematic review and individual participant data meta-analysis of publications reporting the ophthalmologic presentation, clinical exam, and orbital MRI findings in patients with giant cell arteritis and ocular manifestations.

Methods

PubMed and Cochrane databases were searched up to January 16, 2022. Publications reporting patient-level data on patients with ophthalmologic symptoms, imaged with orbital MRI, and diagnosed with biopsy-proven giant cell arteritis were included. Demographics, clinical symptoms, exam, lab, imaging, and outcomes data were extracted. The methodological quality and completeness of reporting of case reports were assessed.

Results

Thirty-two studies were included comprising 51 patients (females = 24; median age, 76 y

SUBMITTER: Guggenberger KV 

PROVIDER: S-EPMC11218900 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature