The role of socio-economic disparities in the relative success and persistence of SARS-CoV-2 variants in New York City in early 2021.

ABSTRACT: Socio-economic disparities were associated with disproportionate viral incidence between neighborhoods of New York City (NYC) during the first wave of SARS-CoV-2. We investigated how these disparities affected the co-circulation of SARS-CoV-2 variants during the second wave in NYC. We tested for correlation between the prevalence, in late 2020/early 2021, of Alpha, Iota, Iota with E484K mutation (Iota-E484K), and B.1-like genomes and pre-existing immunity (seropositivity) in NYC neighborhoods. In the context of varying seroprevalence we described socio-economic profiles of neighborhoods and performed migration and lineage persistence analyses using a Bayesian phylogeographical framework. Seropositivity was greater in areas with high poverty and a larger proportion of Black and Hispanic or

SUBMITTER: Vasylyeva TI 

PROVIDER: S-EPMC11218943 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature